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Antabuse is a medication used to treat chronic alcoholism. It contains active substance disulfiram bis(diethylthiocarbamoyl) which blocks alcohol dehydrogenase (ADH), the enzyme involved into metabolism of ethanol. Consequently blood concentration of acetaldehyde increases and causes unpleasant feelings such as flushing, nausea, vomiting, tachycardia, lowering blood pressure, etc. Consummation of alcoholic beverages becomes extremely unpleasant during treatment with Antabuse.


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